Petri Net based Description and Modeling of Metabolic Pathway
Isaac Barjis and Vijay Gehlot
Summer Computer Simulation Conference 2007 (SCSC 2007)
San Diego, California (USA), July 15-18, 2007
Abstract
System Biology is a rapidly developing discipline which utilizes mathematical and computer science techniques to analyze and interpret biological models. Furthermore advances in analytical and computational technologies are driving the transition to a systems biology that deals with the integrated behavior of biomolecular and metabolic networks. In this paper we use Petri nets to model and simulate the process of carbohydrate metabolic pathways in general and the pentose phosphate pathway in particular. Modeling and simulation of carbohydrate metabolism and pentose phosphate pathway will improve the understanding of the structure and the dynamics of these pathways considerably. Petri nets have been proposed as an effective formalism for Systems Biology and modeling of metabolic pathways.